南京農業大學動物科技學院導師:石放雄

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南京農業大學動物科技學院導師:石放雄

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南京農業大學動物科技學院導師:石放雄 正文

 


姓  名: 石放雄  
性  別:
職  稱: 教授、博士生導師
最高學歷: 博士
畢業院校: 浙江農業大學
專業領域: 動物遺傳育種與繁殖,動物繁殖營養學
聯系方式: E-mail:[email protected] Tel:025-84399112
研究方向: 動物生殖生理與調控,動物繁殖與營養調控,生殖系統的細胞信號傳導等。
參加學術團體及任職情況: 1.家畜繁殖學研究室主任,2.全國中文核心期刊《畜牧與獸醫》雜志社主編,3.《The Open Andrology Journal》編委,4.《Journal of Animal Science Advance》編委,5.江蘇省“333高層次人才培養工程”中青年科學技術帶頭人,6.學校“133優秀學科帶頭人”,7.南京市江寧區科技咨詢委員會專家委員,8.中國畜牧獸醫學會期刊編輯學分會常務理事。
承擔項目: 不詳
論文論著: (1)SCI雜志
1)Liu W, Shi F, Lu L, Zhang C, Liu Y, Zhang J, Tao Z, Shen J, Li G, Wang D, Li J, Tian Y. Effects of linoleic acid and eicosapentaenoic acid on cell proliferation and lipid-metabolism gene expression in primary duck hepatocytes. Mol Cell Biochem. 2011; 352(1-2):19-24.
2)Liu W, Lai S, Lu L, Shi F, Zhang J, Liu Y, Yu B, Tao Z, Shen J, Li G, Wang D, Li J, Tian Y. Effect of dietary fatty acids on serum parameters, fatty acid compositions, and liver histology in Shaoxing laying ducks. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2011; 12: 736-743.
3)Huang P, Zhou Z, Huang R, Zhou B, Wei Q, Shi F. Age-dependent expression of forkhead box O proteins in the duodenum of rats. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2011; 12: 730-735.
4)Zhang W, Shi F. Do genetically modified (GM) crops affect animal reproduction? A review of the ongoing debate. Animal. 2011; 5: 1048-1059. 
5)Liu W, Zhang J, Lu L, Shi F, Niu D, Wang D, YU B, Tao Z, Shen J, Wang D, Tian Y. Effects of perilla extract on productive performance, serum parameters, and hepatic expression of lipid-related genes in Shaoxing ducks. British Poultry Science. 2011; 52(3):381-7.
6)Zhang W, Wei Q, Wang Z, Ding W, Wang W, Shi F. Cell-specific expression and immunolocalization of nitric oxide synthase isoforms and the related nitric oxide/cyclic GMP signaling pathway in the ovary of neonatal and immature rats. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2011; 12: 55-64.
7)Huang R, Qiu X, Shi F, Hughes CL, Lu Z, Zhu W. Effects of Dietary Allicin on Health, Growth Performance of Weanling Piglets, and Reduction in Attractiveness of Faeces to Flies. Animal. 2011; 5: 304-311.
8)Zhang F, Huang J, Li Q, Ju Z, Li J, Shi F, Zhong J, Wang C. Novel single nucleotide polymorphisms (SNPs) of the bovine STAT4 gene and their associations with production traits in Chinese Holstein cattle. African Journal of Biotechnology. 2010; 9:4003-4008.
9)Wang W, Liu H, Ding W, Gong Y, Chen J, Hutz RJ, Mao D, Shi F. Involvement of cell proliferation in the process of follicular atresia in the guinea pig. Tissue and Cell. 2010; 42: 234-241.
10)Wang W, Liu H, Tian W, Zhang F, Gong Y, Chen J, Mao D, Shi F. Morphologic observations and the classification criteria of atretic follicles in guinea pigs. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2010; 11: 307-314.
11)Zhou B, Liu H, Shi F, Wang J. MicroRNA expression profiles of porcine skeletal muscle. Animal Genetics. 2010; 41: 499-508. 
12)Wang H, Huang P, Lie T, Li J, Hutz RJ, Li K, Shi F. Reproductive toxicity of acrylamide-treated male rats. Reproductive Toxicology. 2010; 29: 225-230.
13)Ding W, Wang W, Zhou B, Zhang W, Huang P, Shi F, Taya K. Formation of primordial follicles and immunolocalization of PTEN, PKB and FOXO 3A  proteins in the ovary of fetal and neonatal pigs. Journal of Reproduction and Development. 2010; 56(1): 162-168.
14)Luo J, Tian Y, Tao Z, Yuan Q, Li G, Yuan A, Zou L, Lu L, Shi F. Regulatory expression of peroxisomeproliferator activated receptors genes during fatty liver formation in geese. Agricultural Sciences in China. 2010; 9(1):113-120.
15)Wang Z, Shi F, Jiang Y, Lu L, Watanabe G, Taya K. Changes of cyclic AMP levels and phosphodiesterase activities in the rat ovary. Journal of Reproduction and Development. 2007; 53(4):717-725. (PMID: 17380041).
16)Meng C, Shi F, Huang R, Liu G, Watanabe G, Taya K. Cellular localization of inhibin alpha-subunit, PKB/Akt and FoxO 3a  proteins in the ovary of minipigs. Journal of Reproduction and Development. 2007; 53(2): 229-236. (PMID: 17132910). 
17)Huang R, Shi F, Lei T, Song Y, Hughes CL, Liu G. Effect of the isoflavone genistein against galactose-induced cataracts in rats. Experimental Biology and Medicine. 2007; 232:118-125. (PMID: 17202592). 
18)Wang Z, Shi F. Phosphodiesterase 4 and compartmentalization of cyclic AMP signaling. Chinese Science Bulletin. 2007; 52:34-46.
19)潘玲梅,王恬,石放雄. 肌衛星細胞激活和補給的分子調控與肌肉疾病. 生物化學與生物物理進展 2006; 33(9):811-815.
20)Huo YJ, Wang T, Xu RJ, Macdonald S, Liu G, Shi F. Dietary insulin affects leucine aminopeptidase, growth hormone, insulin-like growth factor I and insulin receptors in the intestinal mucosa of neonatal pigs. Biology of the Neonate. 2006; 89:265-73. (PMID: 16479091).
21)Liu G, Shi F (equal contribution), Blas-Machado U, Yu R, Davis VL, Foster WG, Magoffin DA, Hughes CL. Dietary Galactose Inhibits GDF-9 Mediated Follicular Development in the Rat Ovary. Reproductive Toxicology 2006; 21:26-33. (PMID: 16105726).
22)李學斌, 謝 莊, 石放雄. FOXO 蛋白的修飾與細胞凋亡和癌變.生物化學與生物物理進展 2005; 32:600-606. 
23)Liu G, Shi F, Blas-Machado U, Duong Q, Davis VL, Foster WG, Hughes CL. Ovarian effects of high lactose diet in the female rat. Reproduction, Nutrition, Development 2005; 45:185-192. (PMID: 15954229). 
24)Wang T, Huo Y, Shi F, Xu R, Hutz RJ. Effects of Intrauterine Growth Retardation on Development of the Gastrointestinal Tract in Neonatal Pigs. Biology of the Neonate 2005; 88:66-72. (PMID: 15785017). 
25)Shi F, Perez E, Wang T, Peitz B, Lapolt PS. Stage and Cell-Specific Expression of Soluble Guanylyl Cyclase alpha and beta Subunits, cGMP-Dependent Protein Kinase I-alpha and I-beta, Cyclic Nucleotide-Gated Channel Subunit -1 in  the Rat Testis. Journal of Andrology 2005; 26:258-263. (PMID: 15713832). 
26)Shi F, Stewart RL, Perez E, Chen JY, LaPolt PS. Cell-specific expression and regulation of soluble guanylyl cyclase alpha and beta subunits in the rat ovary. Biology of Reproduction 2004; 70:1552-1561. (PMID: 14749300). 
27)Shi F, LaPolt PS. Relationship between FoxO1 protein levels and follicular development, atresia, and luteinization. Journal of Endocrinology 2003; 179:195-203. (PMID: 14596671).
28)Shi F, Petroff BK, Herath CB, Ozawa M, Watanabe G and Taya K. Serous cysts are a benign component of the cyclic ovary in the guinea pig with an incidence dependent upon inhibin bioactivity. Journal of Veterinary Medical Science 2002; 64(2):129-135. (PMID: 11913549). 
29)Akagi S, Shi F, Kaneko H, Nakanishi Y, Watanabe G, Tsonis CG and Taya K. Ovarian response and hormonal profiles in heifers after immunization and re-immunization against the inhibin alpha-subunit. Journal of Reproduction and Development 2002; 48(6): 599-605. 
30)Petroff BK, Gao X, Ohshima K, Shi F, Son D, Roby KF, Rozman KK, Watanabe G, Taya K and Terranova P. Effects of 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD) on serum inhibin concentrations and inhibin immunostaining during follicular development in female Sprague-Dawley rats. Reproduction Toxicology 2002; 16:97-105. (PMID: 11955940). 
31)Tohei A, Shi F, Ozawa M, Imai K, Takahashi H, Shimohira T, Watanabe G and Taya K. Dynamic changes in plasma concentrations of gonadotropin, inhibin, estradiol and progesterone in cows with ultrasound-guided follicular aspiration. Journal of Veterinary Medical Science 2001; 63:45-50. (PMID: 11217062).
32)Ozawa M, Shi F, Watanabe G, Suzuki AK and Taya K. Regulatory role of inhibin in follicle-stimulating hormone secretion and folliculogenesis in the guinea pig. Journal of Veterinary Medical Science 2001; 63: 1091-1095. (PMID: 11714024).
33)Shi F, Ozawa M, Komura H, Watanabe G, Tsonis CG, Suzuki AK and Taya K. Induction of superovulation by inhibin vaccine in cyclic guinea pigs. Journal of Reproduction and Fertility 2000; 118:1-7. (PMID: 10793620) 
34)Shi F, Mochida K, Ogura A, Matsuda J, Suzuki O, Watanabe G, Hutz RJ, Tsonis CG, Suzuki AK and Taya K. Follicle selection in guinea pigs with active immunization against inhibin alpha-subunit. Life Sciences 2000; 66:2489-2497. (PMID: 10894091).
35)Shi F, Mochida K, Suzuki O, Matsuda J, Ogura A, Tsonis CG, Watanabe G, Suzuki   AK and Taya K. Development of superovulated embryos in guinea pigs with active immunization against inhibin alpha-subunit. Endocrine Journal 2000; 47(4): 451-459. (PMID: 11075726).
36)Shi F, Watanabe G, Trewin AL, Hutz RJ and Taya K. Localization of ovarian inhibin/activin subunits in follicular dominance during the estrous cycle of guinea pigs. Zoological Science 2000; 17(9):1311-1320.
37)Shi F, Mochida K, Matsuda J, Ogura A, Suzuki O, Ozawa M, Watanabe G, Suzuki AK and Taya K. Ovarian localization of immunoglobulin G and inhibin alpha-subunit in guinea pigs following passive immunization against the inhibin a-subunit. Journal of Reproduction and Development 2000;46:293-299. 
38)Shi F, Ozawa M, Komura H, Yang P, Trewin AL, Hutz RJ, Watanabe G and Taya K. Secretion of ovarian inhibin and its physiologic roles in the regulation of follicle-stimulating hormone secretion during the estrous cycle of the female guinea pig. Biology of Reproduction 1999; 60:78-84. (PMID: 9858489).
(2)Medline雜志:
39)曹文; 黃攀; 張磊; 吳紅照; 張郡; 石放雄. 急性熱應激對性成熟雄性小鼠睪丸、附睪、輸精管中熱休克蛋白70表達的影響.中華男科學雜志,2009, 15 (3) : 2002-206.
40)Wang Z, Jiang Y, Lu L, Huang R, Hou Q, Shi F. Molecular mechanisms of cyclic nucleotide-gated ion channel gating. Journal of Genetics and Genomics, 2007; 34(6):477-485. (PMID:17601606)  
41)王皓,葛津瑤,周振琪,王正朝,石放雄。口服丙烯酰胺對雄性大鼠生長發育及生殖機能的影響。中華男科學雜志,2007,13(6):492-497. (PMID: 17615970).
(3)其他雜志:
43)張寶樂,李國勤,章鶴,沈軍達,李進軍,陶爭榮,陳奕春,王德前,陳文標,石放雄,盧立志。鴨BLVRA基因cDNA克隆及其在輸卵管子宮部的mRNA表達量與青殼性狀的相關性分析。畜牧獸醫學報,2010,41(9):1082-1089. 
44)張寶樂,任晉東,李國勤,石放雄,盧立志。鴨蛋殼顏色定量測定與統計學分析。浙江大學學報( 農業與生命科學版) ,2010, 36( 5) : 573~ 577.
45)方天,丁威,張偉,周波,石放雄。豬卵巢發育的組織學觀察及磷酸二酯酶3A的表達研究。南京農業大學學報,2010,33 (6): 101-104.
46)楊岳,王長法,黃金明,仲躋峰,石放雄。奶牛乳腺炎抗性相關候選基因研究進展。家畜生態學報,2010,31(4):101-104. 
47)賈紅敏,盧立志,石放雄,李國勤。動物TLR4基因多態性及其抗病相關性研究進展。生命科學,2010,22(6):546-550.
48)劉瑋孟,盧立志,石放雄,張靜,弓彥,田勇。日糧不同種類脂肪酸對青殼Ⅱ號蛋鴨蛋黃膽固醇含量和肌肉pH值的影響。飼料工業,2010;31(23):18-20. 
49)黃攀,傅春泉,茆達干,石放雄。雌二醇與孕酮奶樣紙片酶免法的建立及應用。畜牧與獸醫,2010;42(7):5-7.
50)陸燕,林波,王恬,石放雄,劉建新. 大蒜油對體外瘤胃發酵甲烷生成和微生物區系的影響. 動物營養學報,2010,22(2):386-392.
51)潘玲梅; 石放雄; 曹文; 張莉莉; 王恬. 一氧化氮信號通路關鍵酶在豬肌肉系統中的定位.南京農業大學學報,2010,33 (2): 79-82.
52)鄒麗麗; 陶爭榮; 張存; 李國勤; 沈軍達; 任晉東; 石放雄; 盧立志. HSP70在急性熱應激蛋鴨脾臟表達變化的研究.中國畜牧雜志,2010,46(30):6-9.
53)曹文,潘玲梅,田谷一善,石放雄.磷酸二酯酶在卵母細胞成熟中的作用.細胞生物學雜志, 2009,31(4): 497-502. 
54)陸燕; 黃攀; 王恬; 石放雄。日糧多不飽和脂肪酸對家畜繁殖性能的影響。中國畜牧獸醫,2009,36(9):23-26. 
55)王皓; 李健; 石放雄. 丙烯酰胺的生殖毒性及其影響機理. 畜牧與獸醫,2009,41(3):96-99. 
56)陸燕; 王恬; 石放雄; 林波. 大蒜素對瘤胃發酵和甲烷產量的影響. 中國飼料,2009, (10):11-13.
57)張芬芬; 王長法; 黃金明; 仲躋峰; 石放雄. 催乳素受體的研究進展. 家畜生態學報, 2009, 30(3):6-9.
58)嚴明; 蔣永清; 石放雄. 奶牛脂肪肝的病理學及防治研究進展. 畜牧與獸醫, 2009, 41(2):92-95. 
59)鄒麗麗; 陶爭榮; 沈軍達; 任晉東; 石放雄; 盧立志。急性熱應激對蛋鴨內臟組織HSP70表達的影響。浙江農業學報,2009,21(4) :332~334. 
60)羅錦標; 田勇; 陶爭榮; 袁青妍; 李國勤; 王德前; 原愛平; 鄒麗麗; 盧立志; 沈軍達; 石放雄。PPAR基因在鵝肥肝形成中的可調節性表達。中國農業科學,2008,41(10):3270-3276. 
61)黃攀; 陸燕; 茆達干; 石放雄. 日糧多不飽和脂肪酸對畜禽肉品質的影響. 畜牧與獸醫, 2008, 40(12): 93-95.
62)鄒麗麗; 王沼智; 李國勤; 陶爭榮; 沈軍達; 楊仲一; 王德前; 田勇; 原愛平; 石放雄; 盧立志. 不同飼養模式下熱應激對蛋鴨的影響. 畜牧與獸醫,2008, 40(5):45-47. 
63)王正朝,鐘靈秀,郭寧,張磊,石放雄。長期飲酒對哺乳動物卵巢功能及其eCG反應性的影響。南京農業大學學報,2008,31:155-158. 
64)殷定忠; 龐訓勝; 王正朝; 蔡治華; 石放雄。免疫與未免疫雞感染MDV后血液部分指標及血漿MDA含量與SOD活性的動態變化。中國獸醫學報,2008;28(9):1047-1050。
65)劉宇濤; 夏薇; 韋笑天; 馬維軍; 周聰; 王偉; 石放雄。脫氫表雄酮誘導大鼠多囊卵巢綜合征的研究。動物醫學進展,2008;29(9):27-29。
66)楊鄭州; 田偉; 王正朝; 石放雄. 長期飲酒對哺乳動物免疫器官生長發育的影響. 家畜生態學報,2008,29(4):65-67.
67)羅錦標; 袁青妍; 陶爭榮; 田勇; 李國勤; 王德前; 原愛平; 鄒麗麗; 盧立志; 沈軍達; 石放雄. 填飼前后鵝PPARs基因組織表達特性的研究. 中國家禽, 2008,30(15):24-27. 
68)李開楨; 曲亮; 黃瑞華; 石放雄; 邱新深; 周波; 劉紅林; 王林云. mRNA差異顯示技術的優化及其在蘇淮豬育種中的應用. 畜牧與獸醫, 2008,40(10):97-101. 
69)殷定忠; 蔡治華; 王正朝; 龐訓勝; 楊峰; 石放雄。硒在雛雞抗MDV感染中的作用及其機制研究。中國獸醫雜志,2008;44(5):26-27。
70)李健,石放雄。PDE5參與平滑肌功能調節的機制。細胞生物學雜志,2008,30:431-434. 
71)曹文,潘玲梅,蔣永清,孟春花,李鍵,田谷一善,石放雄。螯合細胞外鈣離子調控體外培養的大鼠卵巢顆粒細胞成熟的機制。細胞生物學雜志,2008,30:234-238.
72)張高振,吳紅照,方唯威,張郡,申玲玲,譚忠銀,石放雄。長期飲酒對小鼠生長發育及其睪丸功能的影響。中國男科學雜志,2008,22(1):3-6。
73)張聰聰,盧立志,石放雄。載脂蛋白A5低甘油三酯效應的機理。中國動脈硬化雜志,2007:15(12):964-968。
74)Wang Z, Shi Q, Shu G, Shi F. Immunohistochemical studies on ovarian follicular cells of Chinese Holstein Cows. Chinese Jjournal of Histochemistry and Cytochemistry, 2007, 16(5): 521-526. 
75)曹文,石放雄。PI-3K/Akt通路的下游因子磷酸二酯酶3B及其臨床研究。細胞生物學雜志,2007,29(6):800-804.
76)宋亞軍,葛津瑤,梁國旗,檀傳艷,王莉莉,石放雄。高頻飲用牛奶和葡萄糖對雌性大鼠生殖機能的影響。家畜生態學報,2007,28(4):53-56.
77)羅錦標,盧立志,石放雄。日糧膽堿對鵝肥肝形成的影響。畜牧與獸醫,2007,39(4):36-38。
78)周振琪,王恬,石放雄。FOXO轉錄因子調控哺乳動物的細胞周期和凋亡。細胞生物學雜志,2007,29(2):187-190。 
79)王正朝,石放雄。 PDE4與cAMP信號區域化.科學通報2006; 51:2577-2586. 
80)王正朝,羅錦標,石放雄。環核苷酸門控離子通道與疾病發生。動物醫學進展,2006,27(8):1-4。 
81)王正朝,黃瑞華,潘玲梅,李學斌,石放雄。環核苷酸門控離子通道的結構、功能及活性調節。中國生物化學與分子生物學報,2006, 22:282-288。 
82)王正朝,龐訓勝,潘曉燕,王鋒,石放雄。微衛星技術在體細胞克隆動物研究中的應用。家畜生態學報,2006,27(4):14-17。 
83)潘玲梅,周振琪,王恬,石放雄。一氧化氮對動物卵巢細胞中功能蛋白基因表達的調節。家畜生態學報,2006,27(2):92-96。
84)李學斌, 謝莊, 石放雄。FOXO蛋白在動物細胞的分化,增殖,免疫,衰老調節中的作用。中國臨床康復,2006,10:158-162。 85)Wang Z, Xu W, Pang X, Shi F, Wang F. Identification methods of embryonic stem cells. Chinese Journal of Clinical Rehabilitation. 2006; 10: 187-189 (王正朝,許衛華,龐訓勝,石放雄,王鋒。胚胎干細胞的鑒定方法。中國臨床康復,2006,10:187-189). 
86)周振琪,潘玲梅,王恬,石放雄。環鳥苷酸對卵巢細胞功能的調控。細胞生物學雜志,2005, 27:603-606.
(4)書本章節:
1)Zheng-chao Wang, Fang-xiong Shi. Ion Channel Book, Part 2: Individual Ion Channel Characteristics: Intracellular Ligand\Environment-Gated Ion Channels. Ceri. H. Davies and James. N. Kew (Editors). Oxford University Press, UK., 2009.
2)石放雄(副主編).《動物生物技術》(普通高等教育“十一五”規劃教材),蔣思文主編,科學出版社,北京,2009. 
(5)會議論文:
1) Shi F. Cellular localization of the FoxO 3a  protein in the ovary and changed concentrations of intracellular calcium during maturation of granulosa cells in vitro in the pig. The International Symposium on Advances in Modern Biology, Theme: Life Sciences in 21st century, Sept. 11-13, 2009, Nanjing ,  China (Plenary session).
2) Shi F. Regulatory expression of FoxO 3a  proteins in different size of follicles and changed concentrations of intracellular calcium during maturation of granulosa cells in vitro in the pig.5th Annual Conference of Asian Reproductive Biotechnology Society, Nov. 27-29, 2008(Plenary session, 第五屆亞洲繁殖生物技術大會特邀報告,云南昆明)。
3) 王正朝,石放雄.第二信使cAMP/cGMP信號通路元件蛋白在中國荷斯坦奶牛卵巢中的定位研究。中國畜牧獸醫學會動物繁殖學分會第十四屆學術研討會,2008年8月,青島。
4) 孟春花,李健,張芬芬,方天,田偉,石放雄。不同直徑豬卵泡中FoxO 3a 轉錄因子和細胞內鈣離子對卵巢顆粒細胞的調節,中國畜牧獸醫學會動物繁殖學分會第十四屆學術研討會,2008年8月,青島。 
5) Wang Z, Shi F. Role of phosphodiesterase in cyclic nucleotide signaling during ovarian follicular development in the rat.第一屆中華醫學會生殖醫學分會-中國動物學會生殖生物學會聯合年會,2007年4月,杭州。
5) Wang X, Huang K, Shi F (Managing Editor). Proceeding of International Conference on Avian Nutrional and Metabolic Disorders. April 14-17, 2006, Nanjing ,  China. 
6) 石放雄。通過人工受精和胚胎移植傳播的奶牛疾病。第2屆中國奶牛發展大會大會專題報告,內蒙古包頭,2006年6月,pp119-126. 
7) 石放雄。與雌激素有關的功能蛋白基因表達和調控。中國地方豬種保護與利用協作組第3次年會暨學術研討會,2005年11月,江西玉山。
8) 李學斌,王林云,謝莊,石放雄。FoxO1蛋白水平與磷酸化水平。第一屆中國養豬生產和疾病控制技術大會--2005中國畜牧獸醫學會學術年會論文集,2005年4月,山東濟南,pp206-210. 
9) 石放雄。環鳥苷酸對卵巢細胞功能的調控。中國畜牧獸醫學會動物繁殖學分會學術年會,2004年8月,浙江寧波。

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